WHAT HAPPENED IN 1541.
Look what happened the 1541.

King Francis I of France gives Jean-François Roberval a commission to settle the province of New France (Canada) and provide for the spread of the "Holy Catholic faith". (15. January 1541)

Santiago, Chile is founded by Pedro de Valdivia. (12. February 1541)

Francis Xavier leaves Lisbon on a mission to the Portuguese East Indies. (7. April 1541)

Hernando de Soto reaches the Mississippi River and names it Río de Espíritu Santo. (8. May 1541)

Francisco Pizarro is assassinated in Lima by the son of his former companion and later antagonist, Diego Almagro the younger. Almagro is later caught and executed. (26. June 1541)

French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada. (23. August 1541)

The Ottoman Turks capture Buda, the capital of the Hungarian Kingdom. (29. August 1541)

Santiago, Chile, is destroyed by indigenous warriors, led by Michimalonco. (11. September 1541)

After three years of exile, John Calvin returns to Geneva to reform the church under a body of doctrine known as Calvinism. (13. September 1541)

Spanish conquistador Hernando de Soto and his forces enter Tula territory in present-day western Arkansas, encountering fierce resistance. (30. September 1541)

Thomas Culpeper and Francis Dereham are executed for having affairs with Catherine Howard, Queen of England and wife of Henry VIII. (10. December 1541)